Baclofen side effects. Data shows that in past years, alcohol contributed to 22.

Aug 16, 2022 · Baclofen may cause diarrhea, constipation, or dysuria. Damage to the brain and other organ systems. If a person later needs to come off the drug, the doctor will taper the Insomnia, GI upset, salty taste with food, and daytime somnolence with doses above that. Patients with spasticity due to traumatic brain injury should wait at least one year Dec 11, 2022 · Baclofen is used to treat muscle spasticity; it is FDA-approved for managing reversible spasticity, particularly for the relief of flexor spasms, clonus, and concomitant pain, common sequelae of spinal cord lesions, and multiple sclerosis. Three features of ITB Therapy are particularly desirable and important to most patients: What are some other side effects of Baclofen Oral Solution? All drugs may cause side effects. For the active ingredient baclofen. Minor side effects include nausea, headache, dizziness, and fatigue, which often diminish as the body adjusts to the medication. The tablets can be halved if required. In some cases, sudden baclofen withdrawal can cause organ failure and death. 1 May 22, 2023 · Side Effects for Gablofen Spasticity Of Spinal Cord Origin Most Common Adverse Reactions In Patients With Spasticity Of Spinal Origin. By using BNFC, you agree to the licence set out in the BNF Publications End User Licence Agreement. fainting. There's a risk you will not be able to breathe properly, and you may have difficulty waking up. Of the total drug interactions, 27 are major, 339 are moderate, and 1 is minor. The most common types of complications seen with ITB are catheter-related, involving infections (usually Staphylococcus aureus) at a rate of 1% to 5% within the first 6 weeks; a 5% to 15% rate of ITB Therapy delivers baclofen directly into the intrathecal space, thereby bypassing the blood-brain barrier. Using cannabis, heroin or methadone with baclofen will increase the drowsy effects of baclofen. Take this medication by mouth with or without food as directed by your doctor, usually 3 times a day. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Prescribed for Chronic Pain, Pain. dizziness. Sep 25, 2023 · Lyvispah side effects. But your doctor may tell you to take it more or less often, depending on your situation. Baclofen is a GABA B agonist frequently used for spasticity associated with SPS and typically the first choice when benzodiazepines fail to adequately control symptoms. This medicine may be given in the clinic, hospital, or at home. Baclofen no debe utilizarse para tratar espasmos musculares causados por trastornos inflamatorios (reumáticos). Side effects due to baclofen usually occur when the medicine is first started. Baclofen Side Effects. Ozobax ( baclofen) is a gamma-aminobutyric acid (GABA-ergic) agonist indicated for the treatment of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity. nausea. Maintenance dosage for long term continuous infusion: 22 to 1400 mcg/day, with most patients adequately maintained on 90 to 703 mcg/day; there is limited experience Jun 26, 2023 · Q. May 22, 2023 · Lyvispah ( baclofen) is a gamma-aminobutyric acid (GABA-ergic) agonist indicated for the treatment of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity. Swallow the tablets during meals with a glass of water or other liquid. Because of the disabling cognitive side effects associated with high oral doses, intrathecal baclofen (ITB) is often considered for severe spasticity. Find patient medical information for baclofen oral compounding kit on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The most common side effects of baclofen are transient sedation, confusion, muscle weakness, vertigo, nausea, drowsiness, dizziness and fatigue 9. Call your doctor if you or your child have any unexplained muscle pain, tenderness, or weakness, especially with a fever. Common side effects of baclofen are low blood pressure, vomiting, nausea, headache, and seizures. It is reserved for patients unresponsive to oral baclofen therapy, or those who experience intolerable central nervous system side effects at effective doses. It is essential to seek immediate medical attention if you experience any severe or concerning side effects. constipation. 0 out of 10 from a total of 435 ratings on Drugs. Several drugs interact with baclofen. Does Baclofen have any effect on kidneys? Baclofen may cause side effects in patients with normal kidney function which include excessive day time urination (pollakiuria), burning sensation while urinating (dysuria), and loss of bladder control (urinary incontinence). Learn about its warnings, interactions, and how to avoid withdrawal symptoms if you stop using it suddenly. 5–3 hrs after the first baclofen administration in all patients. pounding heartbeat. Dec 21, 2023 · Unsafe side effects have happened when baclofen intrathecal injection was stopped all of a sudden. How to use Baclofen. In 2015, Müller et al. Nov 18, 2023 · Unsafe side effects have happened when Lioresal (baclofen intrathecal injection) was stopped all of a sudden. Along with its needed effects, baclofen (the active ingredient contained in Gablofen) may cause some unwanted effects. Alcohol can increase the nervous system side effects of baclofen, such as irritability, dizziness, and drowsiness. Bio-Baclofen is a centrally acting skeletal muscle relaxant and an antispastic agent with a spinal site of action. 4 Measurement of CSF baclofen concentration shows lumbar to cervical ratio of 4:1, thus avoiding untoward cerebral effects of the intrathecal administered baclofen. Sep 19, 2023 · Bio-Baclofen Uses, Dosage, Side Effects, Food Interaction and all others data. If the dose is too high, muscles can become weak so it’s important to get the balance right between reducing stiffness and not reducing strength in your muscles. One study comparing the two medications found no significant differences in spasticity reduction, but patients receiving tizanidine reported fewer side effects and better overall satisfaction. GABA-B receptor activation by baclofen may produce protective neurological effects. Mar 31, 2023 · Medicines that interact with baclofen may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with baclofen. Side Effects: See also: baclofen side effects in more detail. Complications more specific to the pump and catheter are rare but could include: Pump mechanical failure or malfunction. 0 out of 10 from a total of 437 ratings on Drugs. Check with your doctor immediately if any of the following side effects occur while taking A side effect is usually regarded as an undesirable secondary effect which occurs in addition to the desired therapeutic effect of a drug or medication. Discourage alcohol intake when on baclofen. low blood pressure. However if the side effect is persistent and unpleasant, it may require ceasing the baclofen. The greatest risk posed by mixing alcohol and opioids is lethal overdose. Impaired motor control. Side Effects. Baclofen may be used for patients with multiple sclerosis or spinal cord problems. This information sheet explains what baclofen does, how to give it, and what side effects or problems your child may have when they take this medicine. These include drowsiness, fatigue, dizziness, difficulty sleeping, dry mouth and weakness. ) But older adults may be at higher risk of side effects from baclofen. It is important to talk to a healthcare provider before starting or Mar 13, 2023 · How do side effects of baclofen in older adults compare with those seen in younger adults? Side effects of baclofen in older adults are expected to be the same as those seen in younger adults. Learn more about its uses, interactions, and precautions. You should seek advice from your doctor or pharmacist about taking this medicine. The side effects of baclofen may worsen Adult: Spasticity of spinal or cerebral origin (associated with injury, multiple sclerosis, cerebral palsy) in patients who are unresponsive to oral baclofen or other oral antispastic agents, and/or those who experience unacceptable side effects at effective oral doses: Screening: Initially, 25 mcg or 50 mcg via spinal catheter or lumbar puncture over at least 1 minute, increase the dose by 25 Find medical information for baclofen on epocrates online, including its dosing, contraindications, drug interactions, and pill pictures. This medicine is delivered by a drug pump directly into the spinal fluid of your back. Percocet 10/325 may also be used for purposes not listed in this medication guide. Do not use alcohol while taking baclofen because of the increased risk of drowsiness. Sep 25, 2023 · Baclofen is a skeletal muscle relaxant that treats spasticity and muscle pain in people with certain spinal cord conditions. Jan 17, 2024 · Leakage of spinal fluid. Baclofen can cause a mild sense of well-being and relaxation, especially when large doses are taken. CASE 1: a 23-years-old male presented with hiccup for 5 consecutive days. Jun 26, 2024 · Baclofen Side Effects. Take baclofen with a meal or a snack, and try not to miss any doses. Baclofen abuse can begin when someone has a legitimate prescription for the drug. Abrupt discontinuation of oral baclofen may cause withdrawal symptoms including seizures and hallucinations. Indicated for spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity. When you start this treatment, your doctor will give you a small dose and then gradually increase it. Tizanidine effectively works with spasticity caused by multiple sclerosis‚ an acquired brain injury‚ or a spinal cord injury. While baclofen is generally well-tolerated, it can cause negative medication effects such as drowsiness, dizziness, and weakness. If these effects are mild, they may go away within a The tablets are gluten free, sucrose-free, tartrazine-free and free of other azo dyes. The most common side effect of a baclofen pump is increased weakness. Other common side effects include dizziness which occurs in up to 15 percent of users, nausea in up to 12 percent, confusion in 11 percent, low blood pressure in 9 percent, headaches in 8 percent, insomnia in up to 8 percent, and constipation in 6 percent, frequent urination in up to 6 Jul 16, 2023 · Baclofen withdrawal can be severe and can include symptoms such as hallucinations, psychosis and seizures. Unwanted side effects (eg, hallucinations, seizures, high fever, rhabdomyolysis) may occur if baclofen is stopped suddenly. Do not take this medicine if you are allergic to any of these ingredients. 62% of reviewers reported a positive effect, while 23% reported a negative effect. Along with its needed effects, baclofen (the active ingredient contained in Lioresal) may cause some unwanted effects. Has fixed anxiety, feel fantastic. However, animal studies suggest that higher doses of Baclofen can cause a significant and prolonged increase in blood pressure, heart rate, and arterial dilatation. The most common side-effects are feeling sleepy and problems with mobility. Other signs of baclofen abuse can include central nervous system depression, insomnia, and fatigue. Generic Availability: Lower cost generic. 5. Baclofen is available as an oral tablet and oral solution. com. Up to 63 percent of Baclofen users suffer from drowsiness when using this medication. Data shows that in past years, alcohol contributed to 22. What APO-Baclofen looks like. There is also a potential for baclofen abuse. Baclofen (Noumed) is usually taken in 3 – 4 divided doses throughout the day. This medicine is available only with your doctor's prescription. Dec 30, 2020 · Baclofen side effects. In neurological diseases associated with spasm of the skeletal muscles, the clinical effects of baclofen occur due to baclofen action on reflex muscle Nov 8, 2021 · Baclofen is used to treat spasticity (abnormal muscle tightness and stiffness) from multiple sclerosis, spinal cord injuries, and other spinal cord diseases. Flexeril has an average rating of 6. Pricing and Coupons * Prices are without insurance: We could not find an exact match for this medicine. Aug 4, 2023 · This type of treatment, called intrathecal baclofen (ITB), can help people who have a hard time with side effects of the pill form. In a group of intentional overdoses of oral Apr 14, 2023 · In patients with spinal cord injuries, baclofen and tizanidine have demonstrated effectiveness in managing spasticity. ( 34358487) For spasticity of spinalcord origin, typical doses are 300 – 800 mcg/day. Catheter displacement or blockage. In CSF, baclofen has a half-life of five hours and a duration of action of ten to twelve hours with very little drug returning to the systemic circulation. Avoid stopping baclofen intrathecal injection all of a Tizanidine is an FDA-approved drug for managing spasticity. It can cause drowsiness, dizziness, mental/mood changes, and withdrawal symptoms if stopped suddenly. Jan 28, 2021 · It is thought that baclofen works by inhibiting certain reflexes at the spinal level, meaning it blocks them at the spinal cord. Ozobax may also be of some value in patients with spinal cord injuries and other spinal cord diseases. Early detection of either side effect can help institute a bowel program and relieve them effectively. 15 performed a randomized controlled trial to assess the efficacy and safety of individually titrated high-dose baclofen for the treatment of alcohol dependence. Its actions on the CNS may also cause some of the medicine's side effects. clumsiness, unsteadiness, trembling, or other problems with muscle control. Talk to a healthcare provider if you notice any signs or symptoms of a possible serious side effect, including: Difficulty maintaining your posture, staying upright, walking, or balancing. Reporting side effects. Baclofen side effects include. Some examples of CNS depressants are antihistamines or medicine for hay Oct 1, 2019 · Side effects affect almost half (45%) of people taking baclofen. drowsiness. It can cause side effects such as drowsiness, dizziness, and allergic reactions. Side effects can occur when commencing, decreasing Feb 24, 2010 · Baclofen (Oral) Your child needs to take the medicine called baclofen (say: BAK-loe-fen). Mar 4, 2022 · Some of the general signs of baclofen abuse are difficult to distinguish from side effects resulting from normal use, such as dizziness, weakness, and drowsiness. There are 367 drugs known to interact with baclofen, along with 4 disease interactions, and 1 alcohol/food interaction. The content on the NICE BNFC site (BNFC) is the copyright of BMJ Publishing Group Ltd, the Royal Pharmaceutical Society of Great Britain, and RCPCH Publications Ltd. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. These generally respond to time and simple symptomatic treatment. It can help with muscle spasms, tightness, stiffness, and pain. Symptoms of advanced baclofen withdrawal include high fever, muscle stiffness and changes in mental status. seeing or hearing things that are not there. false sense of well-being. Baclofen puede también utilizarse May 23, 2024 · The daily dose may be reduced by 10% to 20% if patients experience side effects; most patients require gradual increases in dose to maintain optimal response during chronic therapy. Complications with intrathecal baclofen pumps are high, with approximately 21% of pump recipients experiencing some type of adverse drug event. Jun 3, 2021 · Baclofen doses reached a maximum of 30 mg/day, and no hepatic side effects were noted. You may report side effects to Health Canada at 1-866-234-2345. Apr 12, 2023 · Baclofen’s mechanism of action is unique compared to other muscle relaxants, making it a popular choice for individuals with chronic spasticity. 1% of prescription opioid-related overdose deaths. Increase in how much or how often Jun 21, 2024 · Memory problems. Tell your doctor if any of these symptoms are severe or do not go away: dizziness; weakness; confusion; headache; nausea; constipation; difficulty falling asleep or staying asleep; tiredness; frequent urination; Some side effects can be serious. Oct 6, 2022 · Lyflex, Lioresal. 3. Side Effects What are the side effects of Baclofen (Oral) (Oral)?. Sometimes needed 40 to 60 mg four times a day to control bad hiccup flares. mental depression or other mood changes. 0 out of 10 from a total of 232 ratings on Drugs. If you are using the liquid form of You may report side effects to Health Canada at 1-866-234-2345. Do not stop giving Baclofen to your child suddenly as this may cause serious side effects including increased anxiety (worry) behaviour changes, seizures, high Baclofen is a medicine used to help muscles relax (muscle relaxant). Weakness may improve by reducing the dose of baclofen from the pump. If you experience either of the following symptoms, call your Unwanted side effects (eg, hallucinations, seizures, high fever, rhabdomyolysis) may occur if baclofen is stopped suddenly. Ozobax: May also be of some value in patients with spinal cord injuries and other spinal cord diseases. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Sep 20, 2023 · Serious side effects of Gablofen. Hence, it should not be used with medicines that cause similar side effects like pain-relieving opiates. Your doctor may increase your dose by 5 mL every 3 days as needed and tolerated. Your doctor will suggest starting with a small dose and increasing slowly to try to minimise side effects. Jun 17, 2024 · This medication is taken by mouth, typically 3 times a day. For oral dosage form (solution): Adults and children 12 years of age and older—At first, 5 milliliters (mL) 3 times a day for 3 days. Adult: Spasticity of spinal or cerebral origin (associated with injury, multiple sclerosis, cerebral palsy) in patients who are unresponsive to oral baclofen or other oral antispastic agents, and/or those who experience unacceptable side effects at effective oral doses: Screening: Initially, 25 mcg or 50 mcg via spinal catheter or lumbar puncture over at least 1 minute, increase the dose by 25 For baclofen. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Feeling dizzy, sleepy, tired, or weak. National Library of Medicine, side effects of baclofen may include the following: More severe side effects of this drug include difficulty breathing and seizures; medical help should be sought immediately if either of these side effects is experienced. Continue to take baclofen even if you feel well. Hiccup resolved 0. Precautions Before taking baclofen , tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies . You can help ensure medicines are safe by reporting the side effects you experience. 4 out of 10 Bloody or dark urine. This activity outlines the indications, mechanism of action, safe administration, adverse effects Dec 5, 2023 · Baclofen can also be given through a pump that is fitted under the skin. Common baclofen side effects include drowsiness and impaired balance. Baclofen has an average rating of 7. Follow your doctor’s instructions carefully. View baclofen information, including dose, uses, side-effects, renal impairment Sep 20, 2023 · Serious side effects of Lioresal. Oral. Apr 6, 2024 · What are some other side effects of Baclofen Tablets? All drugs may cause side effects. More severe side effects can include confusion, unusual thoughts or behavior, hallucinations, seizures, and an irregular Baclofen may cause side effects. Percocet 10/325 has an average rating of 7. This is to reduce side-effects such as drowsiness. Baclofen also possesses anti-inflammatory properties that may be of Mar 20, 2023 · The incidence of adverse effects with therapeutic baclofen dosing varies between 10 to 65%. However, the dose is usually not more than 80 milligrams (mg) per day (20 mg four times a day). Baclofen also stimulates gastric acid secretion . Stopping the medicine suddenly may cause seizures or side effects including dizziness, diarrhea, nausea, headaches, vomiting, irritability, trouble with sleeping, nightmares, or tingling feelings. A doctor will surgically place the pump and monitor the dose of the medication Baclofen has a boxed warning, the strictest warning from the US Food and Drug Administration (FDA). S. Try searching the Price Guide directly. Get emergency medical help if you have : hives, difficult breathing, swelling of your face, lips, tongue, or throat. This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). The most common side effects of baclofen are nausea, drowsiness, confusion, dizziness and fatigue. Serious Side Effects and Precautions: While less common, Baclofen can also cause more serious side effects, such as hallucinations, confusion, difficulty breathing, and allergic reactions. How to take it . Stopping the medicine too fast can result in unwanted side effects Intrathecal baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. Baclofen may cause side effects which include drowsiness, euphoria, and dysphoria. However, patients on chronic baclofen therapy develop tolerance. Sep 19, 2023 · Baclofen, when used as indicated, improves mobility, increasing levels of independence, and facilitates both passive and active physiotherapy. Remember What Are Side Effects of Baclofen. Some of these side effects have been high fever, mental changes, more spasms, and muscle stiffness. When stopping baclofen, work with your doctor to gradually reduce the dose. As a result, only a fraction of the oral dose is needed to produce efficacy while minimizing systemic side effects. Jul 1, 2024 · Unwanted side effects (eg, hallucinations, seizures, high fever, rhabdomyolysis) may occur if baclofen is stopped suddenly. It can make you go into a very deep sleep. Call your doctor at once if you have: severe drowsiness, breathing problems; confusion, hallucinations; side effects. Baclofen is a medication used to treat muscle spasms caused by certain conditions. 2000mcg/mL (generic, Lioresal, Gablofen) Spasticity. Side effects may vary for each individual depending on the person's disease state, age, weight, gender, ethnicity and general health. Get emergency medical help if you have signs of an allergic reaction to Lyvispah: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Jun 15, 2021 · For spasticity of spinal cord origin, chronic infusion of baclofen injection (intrathecal) via an implantable pump should be reserved for patients unresponsive to oral baclofen therapy, or those who experience intolerable CNS side effects at effective doses. Jan 4, 2024 · Baclofen can cause side effects. Baclofen comes as tablets, as well as oral solutions (including brand names Ozobax DS and Fleqsuvy) and dissolvable granules (brand name Lyvispah) for people who've trouble swallowing tablets. In this trial, individually titrated high-dose baclofen (30–270 mg/day Baclofen se utiliza en adultos y niños de al menos 12 años para tratar el dolor muscular, espasmos y rigidez en las personas con esclerosis múltiple o lesiones o enfermedad de la médula espinal. Baclofen 10 mg tablets: White, oval, flat-faced, bevel-edged tablets scored and engraved "APOB10" on one side. However, many people have no side effects or only have minor side effects. It is a centrally acting alpha-2 receptor agonist. Side effects of baclofen that are different from gabapentin include weakness, headache, seizures, low blood pressure, constipation, confusion, respiratory depression, inability to sleep, and increased urinary frequency or urinary retention. Depression. 47% of reviewers reported a positive effect, while 28% Unwanted side effects (eg, hallucinations, seizures, high fever, rhabdomyolysis) may occur if baclofen is stopped suddenly. Avoid stopping Lioresal (baclofen 1 day ago · Baclofen Side Effects, Dosage & Interactions. Like most muscle relaxants, it reduces the transmission of messages between nerve cells. This allows the muscles to contract less. This can cause advanced withdrawal. Using cocaine or other stimulants like MDMA (ecstasy) and amphetamines with baclofen can also make you drowsy. Jan 30, 2017 · The recommended adult dose for spasticity is 10 to 20 mg orally three to four times daily. chest pain. Baclofen may also be used to relieve other conditions as determined by your doctor. They can help you balance the risks and the benefits of this medicine during pregnancy. Baclofen may cause serious side effects including: mood changes, confusion, depression, and; hallucinations; Get medical help right away, if you have any of the symptoms listed above. In pre- and post-marketing clinical trials, the most common adverse reactions associated with use of intrathecal baclofen which were not seen at an equivalent incidence among placebo-treated patients were: somnolence, dizziness, nausea, hypotension, headache Jul 16, 2023 · Withdrawal symptoms tend to be most severe for patients who use the spinal injection version of baclofen. Baclofen (Lioresal, Kemstro) is a muscle relaxant drug used for treating muscle spasms, rigidity, and pain from conditions such as multiple sclerosis (MS). ringing or buzzing in the ears. Passing out, or loss of consciousness. Seizures. See also: gabapentin side effects in more detail. no Real side effects, haven’t felt like a drink this drug blocks the urge or feeling like alcohol. According to the U. The most common side effects are drowsiness and dizziness. Rarely, these side effects have led to very bad muscle problems, organ problems, and death. For spasticity of cerebral origin, typical doses are 90 – 700 mcg/day. After receiving information on the characteristics, dosing and possible side effects of the drug, all patients signed informed consent before baclofen administration. Baclofen may cause serious side effects. Other uncommon side effects: Muscle or joint pains, rashes, face and ankle swelling, nasal congestion, hot flushes, excessive sweating. Mar 29, 2022 · Acute ingestion of >200-400 mg baclofen is associated with a higher risk of coma, seizure, or intubation. Baclofen Interactions. It has this warning because if you stop taking baclofen abruptly, there is a risk of serious side effects including hallucination, seizures, and even death. It may also activate key receptors in the brain to create a feeling of relaxation and Intrathecal baclofen is also indicated for the management of severe spasticity of the cerebral or spinal original in patients 4 years of age and older. Avoid stopping this drug all of a sudden without talking with your doctor. 7. Check with your doctor immediately if any of the following side effects occur while taking Sep 20, 2023 · Side effects such as hallucinations, confusion or mental depression, other mood or mental changes, and severe drowsiness may be especially likely to occur in elderly patients, who may be more sensitive than younger adults to the effects of intrathecal baclofen. (Older adults are usually considered ages 65 years and older. Mar 13, 2019 · The more common side effects of baclofen oral tablet can include: headaches. Unsafe side effects have happened when this drug was stopped all of a sudden. While baclofen is effective, it is not without its side effects. Extreme drowsiness or weakness, slow heartbeat, trouble breathing. Side effects of baclofen include sleepiness, dizziness, and nausea. Lyvispah may also be of some value in patient with spinal cord injuries and other spinal cord diseases. Lower cost generic. As such, doctors will introduce the drug slowly to find the minimum effective dosage. Drowsiness, dizziness, weakness, headache, constipation, nausea, or vomiting may occur. It delivers the drug right to the spinal cord, so it doesn’t Feb 23, 2022 · One of the rare side effects of Baclofen is that it lowers blood pressure and causes trouble breathing at recommended doses. Avoid abrupt withdrawal (risk of hyperactive state, may exacerbate spasticity, and precipitate autonomic dysfunction including hyperthermia, psychiatric reactions and convulsions; to minimise risk, discontinue by gradual dose reduction over at least 1–2 weeks (longer if symptoms occur)). The dose should be increased and tapered gradually. It has also been shown to be clinically effective in managing patients suffering from chronic neck and Popular comparisons. Although not all of these side effects may occur, if they do occur they may need medical attention. 11. Baclofen also has several off-label uses. Cerebral palsy. Jul 1, 2024 · Baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. . Serious side effects. Trouble sleeping. drowsiness, weakness, dizziness, tiredness, headache, seizures, nausea, vomiting, low blood Baclofen is a muscle relaxant that treats muscle spasms. yg th cd zz yw vf ps jk xb qw